{"id":3870,"date":"2023-01-18T14:54:41","date_gmt":"2023-01-18T14:54:41","guid":{"rendered":"https:\/\/www.institutofertilidadviamed.com\/hospital-santa-angela-de-la-cruz\/clinical-cases\/implantation-failure\/"},"modified":"2026-07-14T16:55:58","modified_gmt":"2026-07-14T16:55:58","slug":"implantation-failure","status":"publish","type":"page","link":"https:\/\/www.institutofertilidadviamed.com\/hospital-santa-angela-de-la-cruz\/en\/clinical-cases\/implantation-failure\/","title":{"rendered":"Treatments for implantation failure in Seville"},"content":{"rendered":"\t\t
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Treatments for implantation failure in Seville: answers when the positive result resists<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tImplantation failure is probably one of the most bewildering moments in an assisted reproduction treatment. There is nothing more frustrating for a couple than undergoing a transfer with \u201cgood-quality\u201d embryos and once again receiving a negative result. \t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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What is implantation failure and when should we investigate?<\/h2>

We speak of recurrent implantation failure when pregnancy is not achieved after several In Vitro Fertilisation, or IVF, attempts using embryos of optimal quality. Although there is no strict consensus on the number of attempts, at our clinic in Seville we propose an in-depth study after 2 or 3 failed embryo transfers. <\/p>

At this point, our team of professionals stops looking only at the surface and analyses the three pillars of success: the embryo, the uterus, or endometrium, and the mother\u2019s systemic environment.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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The embryo factor: beyond appearance <\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tSometimes, an embryo that looks \u201cperfect\u201d visually hides problems that prevent implantation: \t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tGenetic problems: \t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tAn embryo may have very good morphology under the microscope but still present chromosomal alterations. In these cases, Preimplantation Genetic Testing, or PGT-A, is the key tool to ensure that we transfer only healthy embryos. \t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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The endometrial factor: preparing the \u201cnest\u201d<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tEven with the best embryo in the world, if the \u201cground\u201d is not ready, pregnancy will not occur. At IFV Sevilla, we study the endometrium from three critical perspectives: \t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tReceptivity profile: \t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tWe use the most advanced tests to identify the exact window of implantation. Not all women are receptive at the same moment; some need the transfer to be shifted by a few hours in order to coincide with their peak receptivity. \t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMicrobiota and endometritis: \t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tWe analyse the balance of bacteria in the uterus. An altered microbiota or silent inflammation, known as chronic endometritis, may be the invisible cause of embryo rejection. \t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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360-degree vision: a multidisciplinary approach in Seville<\/h2>\nImplantation failure rarely has a single cause. For this reason, the great advantage of being integrated into Viamed Hospital Santa \u00c1ngela de la Cruz is that we have immediate support from other specialties: \t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Poor-quality gametes:<\/h3>

We assess whether egg or sperm quality is the root cause, sometimes considering the use of donor gametes.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Haematology and immunology: <\/h3>

We rule out coagulation problems, or thrombophilias, and immunological factors in which the mother\u2019s body identifies the embryo as a foreign agent.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Anatomical and endocrine causes: <\/h3>

We carefully review the uterine cavity and hormonal balance, including thyroid function, insulin and vitamin D.<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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FAQs: questions about implantation failure<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tIf my embryos are grade A, why am I not getting pregnant?<\/a>\n\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t

Visual quality, or morphology, does not guarantee genetic health or compatibility with the endometrium. That is why, after several failures, more advanced studies should be considered. <\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tIs the endometrial study painful?<\/a>\n\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t

Tests such as endometrial biopsy for receptivity or microbiota assessment are performed quickly in consultation and involve only minimal discomfort, similar to that perceived during menstruation. <\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tWhat chance of success do I have after implantation failure?<\/a>\n\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t

Once we identify the cause, whether it is a displaced implantation window or a coagulation factor, and adjust the protocol, success rates improve considerably. <\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tYour positive result deserves a precision strategy \t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tDo not repeat the same path expecting different results. If you have experienced failed transfers, come to Hospital Santa \u00c1ngela de la Cruz. Let the technology and multidisciplinary vision of our team in Seville find the solution for your Life Project. \t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tREQUEST YOUR IMPLANTATION FAILURE STUDY HERE<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Treatments for implantation failure in Seville: answers when the positive result resists Implantation failure is probably one of the most bewildering moments in an assisted reproduction treatment. There is nothing more frustrating for a couple than undergoing a transfer with \u201cgood-quality\u201d embryos and once again receiving a negative result. What is implantation failure and when […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":3807,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-3870","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nImplantation failure - Instituto de fertilidad Viamed - IFV<\/title>\n<meta name=\"description\" content=\"Repeated implantation failure consists of the failure to achieve a pregnancy after several attempts of assisted reproduction by in vitro fertilisation.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.institutofertilidadviamed.com\/hospital-santa-angela-de-la-cruz\/en\/clinical-cases\/implantation-failure\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" 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