{"id":3874,"date":"2023-01-18T17:10:09","date_gmt":"2023-01-18T17:10:09","guid":{"rendered":"https:\/\/www.institutofertilidadviamed.com\/hospital-santa-angela-de-la-cruz\/clinical-cases\/advanced-maternal-age\/"},"modified":"2026-07-14T16:31:26","modified_gmt":"2026-07-14T16:31:26","slug":"advanced-maternal-age","status":"publish","type":"page","link":"https:\/\/www.institutofertilidadviamed.com\/hospital-santa-angela-de-la-cruz\/en\/clinical-cases\/advanced-maternal-age\/","title":{"rendered":"Treatments for becoming a mother at an advanced age in Seville"},"content":{"rendered":"\t\t
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Treatments for becoming a mother at an advanced age in Seville<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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In recent decades, we have witnessed a profound social change in the Western world. The tendency to postpone motherhood is now a reality, and at Viamed Fertility Institute we understand this perfectly: your Life Project may sometimes require waiting for the right personal or professional moment. However, although society has changed, biology still follows its own timeline. <\/p>

From Viamed Hospital Santa \u00c1ngela de la Cruz, we approach advanced maternal age with a combination of rigorous science and empathy, offering highly complex hospital-based tools so that the time factor does not become an insurmountable obstacle.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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The biology of time: why does fertility decline?<\/h2>

Unlike men, women are born with a finite number of eggs that do not replicate during adult life. This ovarian reserve naturally decreases from birth. But the challenge is not only quantity, but also quality. <\/p>

According to reference studies such as Heffner et al., fertility loss becomes especially critical from an average age of 37. From that point onwards, the probability of pregnancy decreases while the miscarriage rate increases exponentially. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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The challenge of quality: aneuploidies and the meiotic spindle<\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Why do eggs age? The answer lies in cellular machinery. With age, the rate of aneuploidies increases, meaning errors in the number of chromosomes in the egg. This occurs mainly due to failures in the assembly of the meiotic spindle, the structure responsible for separating chromosomes correctly. <\/p>

In addition to these genetic errors, advanced maternal age is associated with:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tOxidative metabolism: \t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tAn increase in cellular oxidation and poorer functioning of natural antioxidant mechanisms.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMorphological alterations: \t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tInadequate maturation of the egg cytoplasm.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tAssociated conditions: \t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tA higher incidence of endometriosis, leiomyomas, or fibroids, and tubal problems that complicate the infertility picture.\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Becoming a mother at 40: reality and possibilities in Seville<\/h2>

This is the question we hear most often in consultation: \u201cCan I become a mother at 40?\u201d The answer is yes, but the approach must be high-resolution. At this age, time is the most valuable resource, so we cannot leave success to chance. <\/p>

To achieve pregnancy at the age of 40, our excellent team of professionals combines treatment for low ovarian reserve with the most advanced embryo selection techniques. The goal is not only to achieve a positive result, but to ensure that the baby is born healthy. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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PGT-A and Time-Lapse with AI: the necessary genetic filter<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tGiven that, from the age of 40, a high proportion of embryos may present chromosomal alterations, at IFV we use cutting-edge technology to identify them:\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tPGT-A, or Preimplantation Genetic Testing: \t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tThrough an embryo biopsy, we analyse the chromosomes of the embryo before transferring it to the uterus. This allows us to rule out embryos with aneuploidies, drastically reducing the miscarriage rate and the risk of chromosomal diseases. \t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tTime-Lapse incubators with Artificial Intelligence: \t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tThese systems allow us to observe embryo development minute by minute. AI helps classify embryos with the highest implantation potential, based on cell division patterns that indicate greater biological viability. \t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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FAQs: questions about advanced maternal age<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t Is pregnancy at an advanced age dangerous?<\/a>\n\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t

Thanks to the highly complex hospital environment of Viamed Hospital Santa \u00c1ngela de la Cruz, risks are reduced through comprehensive prenatal monitoring. We have all medical specialties available to care for both mother and baby. <\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tWhat happens if my ovarian reserve is very low? <\/a>\n\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t

If, after several attempts, the quality of your own eggs does not allow us to obtain healthy embryos, in Seville we offer egg donation programmes with excellent success rates, allowing you to fulfil your dream of becoming parents with complete safety. <\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t<\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tWhy is PGT-A so important from the age of 38 to 40 onwards?<\/a>\n\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t

Because it helps avoid the emotional strain of transferring embryos that we know have a lower probability of leading to an ongoing pregnancy. By selecting only chromosomally healthy embryos, the time needed to achieve pregnancy is considerably shortened. <\/span><\/span> <\/span><\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tYour Life Project does not have to wait any longer\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tChoose science and hospital support in Seville. Do not let statistics hold you back. Come and meet us, and together we will design the technological strategy your motherhood journey needs. \t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tREQUEST YOUR AGE-RELATED FERTILITY CONSULTATION HERE<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Treatments for becoming a mother at an advanced age in Seville In recent decades, we have witnessed a profound social change in the Western world. The tendency to postpone motherhood is now a reality, and at Viamed Fertility Institute we understand this perfectly: your Life Project may sometimes require waiting for the right personal or […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":3807,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-3874","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nTreatments for becoming a mother at an advanced age in Seville - Instituto de fertilidad Viamed - IFV<\/title>\n<meta name=\"description\" content=\"Advanced maternal age is associated with increased oxidative metabolism in the oocyte and a poorer functioning of the antioxidant molecular mechanisms.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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