Haematology, coagulation and fertility

Embryo implantation and the early development of pregnancy depend on multiple biological factors. In addition to embryo quality or endometrial receptivity, adequate blood circulation and correct vascularisation of the uterus also play an important role during the early stages of pregnancy.

The endometrium needs to develop an adequate vascular network to support implantation and early pregnancy growth. When alterations related to coagulation or certain clinical histories exist, it may be necessary to broaden the study through specialist assessment.

In some cases, especially in the presence of recurrent miscarriage or suspected coagulation disorders, the fertility team may recommend the involvement of haematology specialists.

At Viamed Fertility Institute, we work in a multidisciplinary way to assess, on an individual basis, the factors that may influence the reproductive process and pregnancy development.

What does haematology study in fertility?

Haematology is the medical speciality responsible for the study of blood, coagulation and alterations related to the vascular system.

In the reproductive field, the haematologist evaluates possible disorders that may affect the correct functioning of blood circulation during embryo implantation and pregnancy.

The assessment may focus on aspects related to:

Coagulation alterations

Thrombophilias

Formation of small blood vessels

Thrombotic risk

Pregnancy history

Factors that may influence early vascular development in pregnancy

The aim is to identify possible alterations that require specific follow-up or management.

Relationship between coagulation, vascularisation and embryo implantation

Embryo implantation is a complex process that requires an appropriate interaction between the embryo and the endometrium.

During the first stages of pregnancy, important changes take place in uterine vascularisation in order to support blood supply and embryo development.

The formation of small blood vessels and correct circulation contribute to the early development of the placenta and to pregnancy progression.

When there are alterations related to coagulation, these mechanisms may require specific assessment as part of the multidisciplinary fertility study.

When may haematology assessment be recommended?

Haematological assessment is not part of the routine fertility study and is indicated only in certain cases.

The medical team may consider this evaluation in situations such as:

History of recurrent miscarriage

Suspected coagulation alterations

Suspected thrombophilias

Certain personal or family history

Specific analytical alterations

Selected cases in which it is necessary to broaden the reproductive study

The need to perform these tests must always be assessed individually.

Thrombophilias and fertility

Thrombophilias are alterations that may increase the tendency to develop coagulation-related events.

Some thrombophilias are hereditary and others acquired, and their clinical relevance must always be interpreted within the patient’s overall context.

When there is clinical suspicion, the haematologist can study whether these alterations may have implications during pregnancy or require specific follow-up.

Not all patients need thrombophilia testing and not all alterations have the same clinical significance, so assessment must be individualised.

Haematology and recurrent miscarriage

Recurrent miscarriage can have different causes and usually requires a comprehensive assessment.

The study may analyse different factors related to:

Anatomical alterations

Genetic factors

Endocrine alterations

Immunological factors

Coagulation disorders

In certain specific cases, haematological assessment may form part of the diagnostic process to rule out possible associated alterations.

When a disorder is identified, the specialist may establish follow-up and management guidelines during fertility treatment and pregnancy.

Haematological follow-up during pregnancy

When an alteration related to coagulation is detected or there is a specific clinical indication, specialist follow-up may be necessary during pregnancy.

This monitoring makes it possible to follow pregnancy progress and adapt clinical management according to each patient’s needs.

Follow-up is always carried out in coordination between the fertility team and the specialists involved in order to provide comprehensive, personalised care.

A multidisciplinary approach to the study of fertility

Fertility and pregnancy are complex processes in which different medical factors may be involved.

For this reason, at Viamed Fertility Institute we work from a multidisciplinary model in which the assisted reproduction team can coordinate with specialists in haematology, immunology, endocrinology, andrology and psychology when the case requires it.

This approach makes it possible to broaden the study, individualise clinical decisions and provide care adapted to each patient.

Frequently asked questions about haematology and fertility

Embryo implantation and early pregnancy development require adequate vascularisation and blood circulation, so certain disorders may require specialist assessment.

They are alterations related to coagulation that may increase the tendency to develop thrombotic events. Their clinical relevance must be assessed individually.

No. Haematological assessment is reserved for specific situations and does not form part of the usual study in all cases.

It may be considered in cases of recurrent miscarriage, suspected thrombophilias or certain analytical alterations or clinical history.

Yes. When an alteration is detected, the specialist may recommend individualised follow-up and management during pregnancy.

We are here to support you.
We are here to support you.

Dr. Pamela Valdivieso Mejía

gynaecologist and specialist in assisted reproduction

Dr. Silvia Valladares Jiménez

Specialist in Endocrinology and Nutrition

Dr. José Vilar

GYNAECOLOGIST

Ángeles Bretón

CLINICAL EMBRYOLOGIST

Dr. Carlos Javier Vega Reina

GYNAECOLOGIST

Dr. María Miró

IMMUNOLOGIST

Dr. María Eugenia Molina

HEMATOLOGIST

Elena Mantrana Bermejo

Gynecologist. Specialist in Reproductive Medicine

  • Degree in Medicine and Surgery from the University of Seville.
  • Specialty in Obstetrics and Gynecology at Hospital Universitario de Valme, Seville.
  • Master’s Degree in Human Reproduction from the Universidad Rey Juan Carlos.
  • Specialist Physician of the Andalusian Health Service in the South Health Management Area (AGSS) of Seville.
  • Coordinator of the Assisted Human Reproduction Unit of the Hospital Universitario de Valme, Seville.
  • Member of the Human Reproduction Advisory Committee of AGSS of Seville.
  • Member of the working group for the update of the Guide for Assisted Human Reproduction of the Ministry of Health of the Andalusian Regional Government.
  • Tutor of Specialist Doctors in Training of the Teaching Area of the University Hospital of Valme.
  • Clinical Tutor Medical Students University of Seville

Alberto Armijo

Gynecologist. Reproductive Medicine Specialist